Abstract

Motor impairments and limitations in functional performance are common in children with autism spectrum disorder, restricting participation in daily activities. This study aimed to compare the effectiveness of the MIG Program with conventional physical therapy in the development of socio-communicative motor skills and the achievement of functional goals. A mixed-methods randomized clinical trial was conducted with children with autism spectrum disorder aged 6 to 12 years (mean 8.73 ± 1.95; support levels 1 and 2), recruited from rehabilitation clinics in southeastern Brazil. Participants were randomly assigned to the MIG Program, which integrates contextualized functional motor training with narrative grammar strategies and the use of a therapeutic vest, or to conventional physical therapy based on traditional motor approaches. Primary outcomes included fundamental motor skills and functional goal attainment, while secondary outcomes were balance, gross and fine motor skills, and socio-communicative abilities. The RCT protocol was registered in the Brazilian Clinical Trials Registry (RBR-76pk39r), in 21 October 2025. The MIG Program was associated with greater improvements in fundamental motor skills and functional goal attainment compared to conventional physical therapy, with effects maintained at follow-up, as well as with more favorable trends in balance and communication outcomes; however, no clear differences were observed in gross and fine motor skills. Qualitative findings suggested increased engagement, autonomy, and participation in the MIG group. Overall, these preliminary findings indicate that the MIG Program may be a promising approach for supporting functional outcomes in children with autism spectrum disorder, although the results should be interpreted with caution given the small sample size and the number of outcomes assessed.

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