Abstract

Background/Objectives: This cross-sectional observational study was conducted on 146 patients rehabilitated with removable dentures who attended follow-up examinations. Methods: Sociodemographic, medical, prosthetic, and clinical variables were recorded through clinical examination and structured questionnaires. Associations between variables were evaluated using Chi-square and Fisher’s exact tests. Independent predictors were identified through multivariable logistic regression analysis. Results: Denture-related oral mucosal lesions were identified in 81.5% of participants. Denture stomatitis and traumatic ulceration were the most frequently observed lesions. Significant associations were found between lesion occurrence and prosthesis type, nighttime denture wearing, prosthesis stability, and alveolar ridge resorption. Multivariable analysis demonstrated that nighttime denture wearing (OR = 2.84), prosthesis instability (OR = 2.63), complete denture rehabilitation (OR = 1.89), and advanced alveolar ridge resorption (OR = 2.17) were independent predictors of lesion occurrence. Conclusions: A high prevalence of denture-related oral mucosal lesions was observed in this study population; however, the findings should be interpreted within the context of a single-center cross-sectional study.

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